database of RNA elements
regulating nuclear RNA export in mammals
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ExportAid v.1.0 (July 2014) statistics

Collected sequences:
 235  RNA elements increasing export efficiency
  96  RNA elements decreasing export efficiency
  98  neutral sequences


Species the sequences belong to:
Human:   27       EIAV:   10       HIV:   138	    KSHV:    2       WHV:       2
Mouse:   43       FIV:     1       HPV:    16       MPMV:    9       Synthetic: 6
ALV:      5       HBV:    20       HSV:    15       RSV:    25       
CAEV:     3       HERV-K:  2       HTLV:   31	    SRV:    46

The following table shows ExportAid contents in detail:

ORGANISM

RNA ELEMENT

COUNT

ALV (Avian Leukosis Virus)

CTE (Constitutive Transport Element)

5

CAEV (Caprine Arthritis-Encephalitis Virus)

RRE-C (Rev-Responsive Element)

1

part of genome/synthetic sequence

2

EIAV (equine infectious anemia virus)

RRE (Rev-Responsive Element)

10

FIV (Feline Immunodeficiency Virus)

RRE (Rev-Responsive Element)

1

HBV (Hepatitis B Virus)

PRE (Posttranscriptional Regulatory Element, also HPRE)

42

export promoting domain Beta

10

PPD1 - polypyrimidine domain 1

9

PPD2 - polypyrimidine domain 2

9

HBV element

3

part of genome/synthetic sequence

3

HERV-K (Human Endogenous RetroVirus type K, also HTDV)

K-RRE (Rev-Responsive Element)

2

HHV-8 (Human HerpesVirus type 8)

KSHV element

2

HIV-1 (Human Immunodeficiency Virus type 1)

INS (Inhibitory/Instability Sequence, also CRS or IR)

77

RRE (Rev-Responsive Element)

65

part of genome/synthetic sequence

16

HIV-2 (Human Immunodeficiency Virus type 2)

INS (Inhibitory/Instability Sequence, also CRS or IR)

1

part of genome/synthetic sequence

6

HPV (Human PapillomaVirus)

part of genome/synthetic sequence

16

HSV-1 (Herpes Simplex Virus type 1)

PPE (Pre-mRNA Processing Enhancer)

15

HTLV-1 (Human T-Lymphotropic Virus Type 1)

CIE (Cis-acting Inhibitory Element)

21

RxRE (Rex-responsive element, also XRE)

7

part of genome/synthetic sequence

7

Human

CAR (Cytoplasmic Accumulation Region)

10

CTE (Constitutive Transport Element)

7

CJE (c-Jun gene Enhancer)

3

eIF4E-SE (eIF4E Sensitive Element)

3

SSCR (Signal Sequence Coding Region)

2

PRE (Posttranscriptional Regulatory Element)

1

part of genome/synthetic sequence

1

Mouse

RTE (RNA Transport Eelement)

24

MTE (musD Transport Element)

8

H2a element

5

SSCR (Signal Sequence Coding Region)

3

part of genome

3

MPMV (Mason Pfizer Monkey Virus)

CTE (Constitutive Transport Element)

9

RSV (Rous Sarcoma Virus)

DR (Direct Repeat)

24

part of genome

1

SRV-1 (Simian Retrovirus 1)

CTE (Constitutive Transport Element)

44

SRV-2 (Simian Retrovirus 2)

CTE (Constitutive Transport Element)

2

WHV (Woodchuck Hepatitis Virus)

WPRE (WHV Posttranscriptional Regulatory Element)

2

Synthetic sequences

6








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Polytechnic University of Marche, Italy | 2014